Food allergies: Tracking the enemy within
David Anderson, Krzysztof Maruszewski, Franz Ulberth, Andrew Thomas Clark, Elizabeth Naomi Clare Mil, 31 views

Around 2% of adults (and 8% of children) suffer from food allergies across the globe. For some, the intake of even small amounts of an allergen can cause serious health problems - some of which can be life-threatening. To date there is no effective treatment available. Science provides the basis for food safety, while legislation ensures that appropriate controls are made to protect consumers. Incidences of food allergies appear to be increasing, and some argue that consumer fear and avoidance of certain foodstuffs may actually feedback and contribute to this increase. The scope of this symposium will range from suitable analytical methodology for the detection of allergen traces to policy requirements, health issues and communication.

Understanding and predicting functional responsiveness to physical activity in humans: a systems bio
Carl Johan Sundberg, Claude Bouchard, Jamie Timmons, 61 views

Cardiovascular disease, obesity and diabetes are – in part – lifestyle dependent diseases, and constitute a main healthcare burden. Low aerobic capacity is one of the strongest risk factors for development of cardiovascular disease and premature death in mammals. Exercise, the sole strategy for increasing aerobic capacity in humans, affects many organs and tissues in a beneficial way. The adaptations are mediated through various changes in tissue environment which influence protein modifications and gene expression. Regular physical activity in humans affects the activity (mRNA copy number) of around 1000 genes and several RNA interference mechanisms which through complex networks regulate adaptation.

Still, training is ineffective in a significant number of people. The molecular governors of a low or high propensity for aerobic capacity adaptation are unknown, and population genetics alone has not easily resolved the genetic variants that quantitatively contribute to cardiorespiratory adaptation. In this session, genetic, epigenetic and genomic findings that can explain parts of the inter-individual variation will be discussed. These approaches to identify high- and low-responders will be discussed in the larger context of “personalised medicine”. Finally, the possibility that variations in responsiveness to life style interventions play a role for health outcomes and the risk for premature death will be discussed from health care system and ethical perspectives.

Of genes and bodies: Developmental perspectives in vertebrate evolution
Naoki Namba, Elisabetta Tola, Ann Burke, Shigeru Kuratani, Filippo Rijli, 149 views
The field of evolutionary developmental biology has traditionally striven to explain the evolutionary diversity of animals by focusing on molecular-level changes in developmental mechanisms. But the tendency has been to look at embryo-wide patterns known as body plans, which differ only at very broad taxonomic levels, such as phyla. This wide-view approach, however, does not fully address some of the best-known evolutionarily-determined innovations, such as the giraffe’s neck, the elephant’s trunk, or the bat’s wing, which are much more specific in terms of both the taxa and the anatomic structures involved. This is not to say that such questions are beyond the scope of molecular genetics, but rather that, by focusing on the cellular and molecular levels, modern developmental biology is too often uninformed by a solid grasp of comparative gross anatomy. In this session, we will highlight some of the connections between developmental changes at the molecular level and changes in the anatomical organization in vertebrates over evolutionary time.
Plants for sustainable food supply
Dorothée Bongaerts, Metzlaff Karin, Pere Puigdomènech, Chiara Tonelli, Wilhelm Gruissem, 35 views

The Millennium Development Goals set in the 1990s aimed at reducing by half the number of undernourished by 2015, but it looks like they won't be achieved. The most probable scenarios of population growth predict a world population of 9 billion by 2050, living mostly in 400 megacities of more than 10 million inhabitants. In this context food security, food safety and food health appear as both essential and hard to achieve goals for agricultural production in the next future.

But present efforts to fulfill the need of food production may hinder adequate food availability for future generations, taking into account the effect of agriculture on soil and water use and pollution, and the way agriculture impacts climate change. Therefore, the sustainability of present practices is also important when taking decisions on agricultural policies. New important advances are being produced through the application of molecular genetics to plant biology including basic knowledge on plant productivity, resistance to pathogens or tolerance to adverse conditions. The availability of an increasing number of plant genomes, the analysis of the genetic basis of the variability of crop populations or new crops, and the genetic modification of plants provide tools that may help humankind in tackling this fundamental task.

New comparable data on young researcher's mobility patterns available: what are the consequences for
Ing-Marie Ahl, Wolfgang Eppenschwandtner, Dagmar Meyer, Snezana Krstic, Karoline Holländer, Giancarl, 55 views
Why do doctoral candidates go abroad? What are the most important obstacles they still face? To which extent do links to their home country persist? Do mobile researchers want to return, stay, or move to a further country? Which type of mobility is most common and is appropriate fund- ing available? These kinds of questions have been subject to speculation so far. With the results of a recent survey conducted by Eurodoc, the European Council of doctoral candidates and junior researchers, in cooperation with INCHER, a HE research institute in Kassel (DE), we now have a clearer picture. Eurodoc started this major under- taking in 2008 to counteract the shortage on comparable data on crucial topics like motives for pursuing a doctor- ate, career paths, funding, supervision, generic skills and mobility. Also, a number of other studies regarding researchers’ mobility and framework conditions have recently been conducted; they are complementary in that they concen- trate on a different target group, or examine different questions. The session will provide an overview on data which is currently available. The session will be closed by the presentation of an Italian best practice in the survey and analysis of data concerning University degrees and graduates and PhDs employability: AlmaLaurea.
The role of science and expertise in the environmental disputes
Dario Padovan, Simone Arnaldi, Yannick Barthe, Luigi Pellizzoni, Brian Wynne, 42 views

The reproductive basis of highly differentiated societies is increasingly dependent on knowledge and expertise as well as on equally specialized roles and institutions. In these societies the problem of the political decision is particularly delicate, because those who decide have almost always a deficit of knowledge and expertise related to the complexity of the relevant field of action. Hence the need to use ad hoc experts. This problem pervades many areas of policy choice, such as major infrastructures for mobility, technologies for energy production, environmental risks like climate change, genetic engineering, measures for environmental transition. Basically, we wonder if scientific expertise might be used in decision-making processes in a neutral and impartial way, and if the dichotomy between "democracy" and "expertocracy" can be resolved.

Experts have long been trapped in a perpetual dialogue within their community, but recently the role of pressure groups and bottom-up actors has increased. This workshop will analyze issues such as: expertise and society; expertise and definition of risk; expertise and decision making; expertise and environmental transition; models of expertise; mass-media, language, and rhetorical expertise; genealogies of expertise; expertise, trust and credibility.

State of the art nanofood technology: Risks and benefits
Hermann Stamm, Elke Anklam, Qasim Chaudhry, Thane S. Thurmond, 50 views

Recent opinion polls regarding nanotechnology applications identify one particular sensitive area: the use of nanotechnology in food and feed. Consumer groups who demonstrate, in general, a positive attitude towards nanotechnology including applications in many consumer products are very negative towards nanotechnology in food.

The advent of nanotechnologies has brought enormous new prospects to a wide range of industrial sectors. At the same time, these pioneering processes, materials, and applications have raised fresh concerns over their safety to human health and the environment. Particularly sensitive areas of application include medicine, personal care products, agriculture and food, as well as those applications that involve the deliberate large-scale release of nanoparticles into the environment, such as water treatment and remediation of polluted soils.

This session will focus on state-of-the-knowledge studies of nanotechnology applications for the food sector, identify current knowledge gaps, and suggest possible ways forward. We will discuss the potential benefits and risks of the new technology and consider strategies on how to communicate them to the public without jeopardizing the wider benefits of the new technology to society. The session also addresses the apparent global absence of a nano-specific regulation.

DNA patenting: Truths and fears
David Merino, Daniele Paci, Robert Cook-Deegan, Michael Hopkins, Isabelle Huys, 21 views

Misunderstanding and widespread feelings of fear and danger still surround the issue of DNA patenting. The 1998 European Directive on protection of biotechnological inventions requires EU member states to recognise isolated genes and nucleotide sequences as patentable inventions. Recent rulings of the Board of Appeal of the European Patent Office have illustrated that patents can also be granted for methods of genetic testing without claiming genes themselves. These rulings upheld patents granted for BRCA1-related cancer tests, in the face of considerable opposition from European scientists, who consider DNA patents as a barrier to the progress of genomic research. However, there is not much empirical evidence on how patenting is affecting clinical genetic testing.

Two independent in-depth studies mapping the complex landscape of diagnostic DNA patents in the US and Europe have recently been conducted. These will be presented with a view to discussing the barriers, the opportunities, the actual and potential threats of DNA patenting trying to address some of the following key questions raised by the scientific world and by society: Is patenting affecting accessibility to genetic testing? Are prices higher because of the requirement of licenses? Is there a visible impact on test development as a result of patenting? Is DNA patenting a fair and reasonable way to encourage and protect innovation, or is it a threat to patient rights?

Scientific cultures across Europe: Similarities and differences
Brian Trench, Martin Bauer, Massimiano Bucchi, Esa Valiverronen, 73 views

How alike or unlike each other are European countries in terms of their “scientific culture”? Can we describe and measure scientific culture by means of opinion and attitude surveys? How do the ideologies and belief systems, including the prevailing religious beliefs, influence the scientific culture of individual countries? These and other questions will be explored in this session which will examine similarities and differences in the scientific culture of selected European countries, principally Italy, Finland and Ireland, and of the European Union as a whole, as evidenced principally in Eurobarometer surveys. Drawing also on national surveys on public attitudes to science and technology and analyses of media coverage of science and technology, the panel will aim to characterise the scientific culture of these countries.

The panel will consider historical trends and regional patterns in responses to surveys over three decades on science and technology generally and on particular issues. The panelists are social scientists and communication specialists with a particular interest in perceptions and representations of science and technology, and experience in working directly with natural scientists on science-in-society and communication projects. Those attending the session, of whatever disciplinary background, will be invited to join the discussion on the shaping of a country’s scientific culture, which will also be framed in terms of national and supra-national policy.

Closing the loop: From body to mind and from mind to body
Marcello Costa, Fabrizio Benedetti, Vittorio Gallese, Donatella Marazziti, 31 views

Most people have the feeling of having conscious experiences (Descartes’ res cogitans) and in parallel of being well immersed in a physical world (Descartes’ res extensa). The ancient problem of how the mind emerges in living organisms has divided generations of philosophers and scientists alike. Neuroscience is beginning to throw some light on this problem by recognising that consciousness emerges in parallel with the brain as it develops in an intimate relationship with the body and via it with the external world. This interaction occurs both ways with exposure to the world shaping the brain/mind and with the brain and mind acting in the world. This mutual interaction can be regarded as a loop. Traditionally each arm of this loop has been considered in isolation. The emergence of the “self” depends so much on the ongoing experience of the world. The influence of our brain on our behaviour is a well accepted concept. However, how the neural circuits of the brain with their specific chemical neurotransmitters control behaviour is only at its infancy.

In this session we will clarify how this occurs in determining impulsive and affective behaviour; discuss the influence of the mind over the body focusing on the so called “placebo” effect; underline the remarkable ability of humans to readily accept what other humans do thanks to “mirror neurons”, the discovery of which has opened an entire new field of research on the bases of the “social brain” and its relation with the body. Finally we will discuss with the audience the implications for society of the dynamics of the full experiential loops from body to mind and from mind to body.

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